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Renal inner medullary prostaglandin synthesis. A calcium-calmodulin-dependent process suppressed by urea.

Previous studies have demonstrated that hyperosmolar NaCl and mannitol stimulate immunoreactive prostaglandin E (iPGE) production by slices of inner medulla (IM), whereas urea inhibits this process. In the present study, the roles of Ca2+ and calmodulin in the control of PGE synthesis in IM and the...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Principais autores: Craven, P A, Studer, R K, Derubertis, F R
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 1981
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370854/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6792221/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110308
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