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Prevention of TGFβ induction attenuates angII-stimulated vascular biglycan and atherosclerosis in Ldlr(−/−) mice(1)

Angiotensin II (angII) accelerates atherosclerosis, but the mechanisms are not fully understood. The aim of this study was to determine whether TGFβ is required for angII-induced atherosclerosis. Ldlr-null mice fed a normal chow diet were infused with angII or saline for 28 days. A single injection...

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Autori principali: Tang, Tao, Wilson, Patricia G., Thompson, Joel C., Nelson, Christina, Yoder, Meghan H., Tannock, Lisa R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708375/
https://ncbi.nlm.nih.gov/pubmed/23749984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.P040139
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