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Mechanistic target of rapamycin controls homeostasis of adipogenesis

Signaling mediated by the mechanistic target of rapamycin (mTOR) is believed to play a critical and positive role in adipogenesis, based on pharmacological evidence and genetic manipulation of mTOR regulators and targets. However, there is no direct genetic evidence for an autonomous role of mTOR it...

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Autores principales: Yoon, Mee-Sup, Zhang, Chongben, Sun, Yuting, Schoenherr, Christopher J., Chen, Jie
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708366/
https://ncbi.nlm.nih.gov/pubmed/23740969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M037705
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