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Clearance and Phosphorylation of Alpha-Synuclein Are Inhibited in Methionine Sulfoxide Reductase A Null Yeast Cells

Aggregated α-synuclein and the point mutations Ala30Pro and Ala53Thr of α-synuclein are associated with Parkinson’s disease. The physiological roles of α-synuclein and methionine oxidation of the α-synuclein protein structure and function are not fully understood. Methionine sulfoxide reductase A (M...

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Main Authors: Oien, Derek B., Shinogle, Heather E., Moore, David S., Moskovitz, Jackob
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708264/
https://ncbi.nlm.nih.gov/pubmed/19653131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12031-009-9274-8
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