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Decreased Phosphorylation and Increased Methionine Oxidation of α-Synuclein in the Methionine Sulfoxide Reductase A Knockout Mouse

Previously, we have showed that overexpression of methionine-oxidized α-synuclein in methionine sulfoxide reductase A (MsrA) null mutant yeast cells inhibits α-synuclein phosphorylation and increases protein fibrillation. The current studies show that ablation of mouse MsrA gene caused enhanced meth...

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Bibliografische gegevens
Hoofdauteurs: Oien, Derek B., Carrasco, Gonzalo A., Moskovitz, Jackob
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: SAGE-Hindawi Access to Research 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3275937/
https://ncbi.nlm.nih.gov/pubmed/22332004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/721094
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