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The basis for limited specificity and MHC restriction in a T cell receptor interface
αβ T cell receptors (TCRs) recognize peptides presented by major histocompatibility complex (MHC) proteins using multiple complementarity determining region (CDR) loops. TCRs display an array of poorly understood recognition properties, including specificity, cross-reactivity, and MHC restriction. H...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3708045/ https://ncbi.nlm.nih.gov/pubmed/23736024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2948 |
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