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Transcriptional Repression of Bim by a Novel YY1-RelA Complex Is Essential for the Survival and Growth of Multiple Myeloma

Multiple Myeloma (MM) is an incurable plasma cell cancer that is caused by several chromosomal translocations and gene deletions. Although deregulation of several signaling pathways including the Nuclear Factor-Kappa B (NF-κB) pathway has been reported in MM, the molecular requirement and the crosst...

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Main Authors: Potluri, Veena, Noothi, Sunil K., Vallabhapurapu, Subrahmanya D., Yoon, Sang-Oh, Driscoll, James J., Lawrie, Charles H., Vallabhapurapu, Sivakumar
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707888/
https://ncbi.nlm.nih.gov/pubmed/23874387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066121
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