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Molecular analysis of the beta-thalassemia phenotype associated with inheritance of hemoglobin E (alpha 2 beta2(26)Glu leads to Lys).

Inheritance of the gene for betaE-globin is associated with hypochromia and microcytosis, reminiscent of typical heterozygous beta-thalassemia. Patients with hemoglobin (Hb)E-beta-thalassemia exhibit clinical phenotypes of severe beta-thalassemia, a circumstance not encountered in other compound het...

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Autors principals: Benz, E J, Berman, B W, Tonkonow, B L, Coupal, E, Coates, T, Boxer, L A, Altman, A, Adams, J G
Format: Artigo
Idioma:Inglês
Publicat: 1981
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC370779/
https://ncbi.nlm.nih.gov/pubmed/6166632
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