The Atypical Guanine Nucleotide Exchange Factor Dock4 Regulates Neurite Differentiation through Modulation of Rac1 GTPase and Actin Dynamics

Precise regulation of neurite growth and differentiation determines accurate formation of synaptic connections, whose disruptions are frequently associated with neurological disorders. Dedicator of cytokinesis 4 (Dock4), an atypical guanine nucleotide exchange factor for Rac1, is found to be associa...

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Bibliographic Details
Main Authors: Xiao, Yangui, Peng, Yinghui, Wan, Jun, Tang, Genyun, Chen, Yuewen, Tang, Jing, Ye, Wen-Cai, Ip, Nancy Y., Shi, Lei
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Neurobiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707701/
https://ncbi.nlm.nih.gov/pubmed/23720743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.458612
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