Squeezing at Entrance of Proton Transport Pathway in Proton-translocating Pyrophosphatase upon Substrate Binding

Homodimeric proton-translocating pyrophosphatase (H(+)-PPase; EC 3.6.1.1) is indispensable for many organisms in maintaining organellar pH homeostasis. This unique proton pump couples the hydrolysis of PP(i) to proton translocation across the membrane. H(+)-PPase consists of 14–16 relatively hydroph...

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Detalhes bibliográficos
Main Authors: Huang, Yun-Tzu, Liu, Tseng-Huang, Lin, Shih-Ming, Chen, Yen-Wei, Pan, Yih-Jiuan, Lee, Ching-Hung, Sun, Yuh-Ju, Tseng, Fan-Gang, Pan, Rong-Long
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Enzymology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707635/
https://ncbi.nlm.nih.gov/pubmed/23720778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.469353
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