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A novel phenotype for the dynein heavy chain mutation, Loa: Altered dendritic morphology, organelle density, and reduced numbers of trigeminal motoneurons
Dynein, the retrograde motor protein, is essential for the transport of cargo along axons and proximal dendrites in neurons. The dynein heavy chain mutation, Loa, has been reported to cause degeneration of spinal motor neurons, as well as defects of spinal sensory proprioceptive neurons, but cranial...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3707314/ https://ncbi.nlm.nih.gov/pubmed/22684941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cne.23085 |
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