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P22 viral capsids as nanocomposite high-relaxivity MRI contrast agents

Attachment of multiple chelated Gd(3+) ions to the interior of bacteriophage P22 viral capsids afford nanoscale MRI contrast agents with extremely high relaxivity values. Highly fenestrated ‘wiffleball’ morphology is unique to P22 and assures water exchange between the environment and interior cavit...

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Autors principals: Qazi, Shefah, Liepold, Lars O., Abedin, Md Joynal, Johnson, Ben, Prevelige, Peter, Frank, Joseph A., Douglas, Trevor
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707300/
https://ncbi.nlm.nih.gov/pubmed/22656692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp300208g
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