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P22 viral capsids as nanocomposite high-relaxivity MRI contrast agents

Attachment of multiple chelated Gd(3+) ions to the interior of bacteriophage P22 viral capsids afford nanoscale MRI contrast agents with extremely high relaxivity values. Highly fenestrated ‘wiffleball’ morphology is unique to P22 and assures water exchange between the environment and interior cavit...

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Detalhes bibliográficos
Main Authors: Qazi, Shefah, Liepold, Lars O., Abedin, Md Joynal, Johnson, Ben, Prevelige, Peter, Frank, Joseph A., Douglas, Trevor
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707300/
https://ncbi.nlm.nih.gov/pubmed/22656692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp300208g
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