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P22 viral capsids as nanocomposite high-relaxivity MRI contrast agents

Attachment of multiple chelated Gd(3+) ions to the interior of bacteriophage P22 viral capsids afford nanoscale MRI contrast agents with extremely high relaxivity values. Highly fenestrated ‘wiffleball’ morphology is unique to P22 and assures water exchange between the environment and interior cavit...

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Bibliografiske detaljer
Main Authors: Qazi, Shefah, Liepold, Lars O., Abedin, Md Joynal, Johnson, Ben, Prevelige, Peter, Frank, Joseph A., Douglas, Trevor
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707300/
https://ncbi.nlm.nih.gov/pubmed/22656692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp300208g
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