Pyruvate Dehydrogenase Complex Activity in Normal and Deficient Fibroblasts

Pyruvate dehydrogenase complex (PDC) activity in human skin fibroblasts appears to be regulated by a phosphorylation-dephosphorylation mechanism, as is the case with other animal cells. The enzyme can be activated by pretreating the cells with dichloroacetate (DCA), an inhibitor of pyruvate dehydrog...

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Publié dans:	J Clin Invest
Auteurs principaux:	Sheu, Kwan-Fu Rex, Hu, Chii-Whei C., Utter, Merton F.
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Clinical Investigation 1981
Sujets:	Articles
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370714/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6262377/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI110176
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