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Ancient evolutionary origin of diversified variable regions demonstrated by crystal structures of an immune-type receptor in amphioxus

Although the origins of genes encoding the rearranging binding receptors remain obscure, it is predicted that their ancestral forms were nonrearranging immunoglobulin-type domains. Variable region–containing chitin-binding proteins (VCBPs) are diversified immune-type molecules found in amphioxus (Br...

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Hlavní autoři: Hernández Prada, José A, Haire, Robert N, Allaire, Marc, Jakoncic, Jean, Stojanoff, Vivian, Cannon, John P, Litman, Gary W, Ostrov, David A
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707131/
https://ncbi.nlm.nih.gov/pubmed/16799561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni1359
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