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Polymorphism at the C-reactive protein locus influences gene expression and predisposes to systemic lupus erythematosus
Relative deficiency of pentraxin proteins is implicated in the pathogenesis of systemic lupus erythematosus. The C-reactive protein (CRP) response is defective in patients with acute flares of disease, and mice with targeted deletions of the serum amyloid P component gene (Sap) develop a lupus-like...
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| Autores principales: | , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2003
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3707088/ https://ncbi.nlm.nih.gov/pubmed/14645206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddh021 |
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