CD70–CD27 ligation between neural stem cells and CD4(+) T cells induces Fas–FasL-mediated T-cell death

INTRODUCTION: Neural stem cells (NSCs) are among the most promising candidates for cell replacement therapy in neuronal injury and neurodegenerative diseases. One of the remaining obstacles for NSC therapy is to overcome the alloimmune response on NSCs by the host. METHODS: To investigate the mechan...

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Detalhes bibliográficos
Main Authors: Lee, Eun Mi, Hurh, Sunghoon, Cho, Bumrae, Oh, Kook-Hwan, Kim, Seung U, Surh, Charles D, Sprent, Jonathan, Yang, Jaeseok, Kim, Jae Young, Ahn, Curie
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706991/
https://ncbi.nlm.nih.gov/pubmed/23692980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/scrt206
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