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Multiplex target capture with double-stranded DNA probes

Target enrichment technologies utilize single-stranded oligonucleotide probes to capture candidate genomic regions from a DNA sample before sequencing. We describe target capture using double-stranded probes, which consist of single-stranded, complementary long padlock probes (cLPPs), each selective...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shen, Peidong, Wang, Wenyi, Chi, Aung-Kyaw, Fan, Yu, Davis, Ronald W, Scharfe, Curt
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706973/
https://ncbi.nlm.nih.gov/pubmed/23718862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm454
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