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Dexamethasone Induces a Putative Repressor Complex and Chromatin Modifications in the CRH Promoter
Glucocorticoids down-regulate expression of hypothalamic CRH; however, mechanisms by which they do so are not fully understood. The proximal promoter cAMP response element, negative glucocorticoid response element (nGRE), and methylated CpG islands all play a role in crh down-regulation. Dexamethaso...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Endocrine Society
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3706841/ https://ncbi.nlm.nih.gov/pubmed/23671328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2013-1079 |
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