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Estradiol Regulates Corticotropin-Releasing Hormone Gene (crh) Expression in a Rapid and Phasic Manner that Parallels Estrogen Receptor-α and -β Recruitment to a 3′,5′-Cyclic Adenosine 5′-Monophosphate Regulatory Region of the Proximal crh Promoter

In the central nervous system, CRH regulates several affective states. Dysregulation of neuronal crh expression in the paraventricular nucleus of the hypothalamus correlates with some forms of depression, and amygdalar crh expression may modulate levels of anxiety. Because estrogens modulate these s...

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Bibliografiske detaljer
Main Authors: Lalmansingh, Avin S., Uht, Rosalie M.
Format: Artigo
Sprog:Inglês
Udgivet: The Endocrine Society 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194609/
https://ncbi.nlm.nih.gov/pubmed/17947358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-0372
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