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Novel cancer drivers: mining the kinome

Large-scale cancer genome studies are unveiling significant complexity and heterogeneity even in histopathologically indistinguishable cancers. Differentiating 'driver' mutations that are functionally relevant from 'passenger' mutations is a major challenge in cancer genomics. Wh...

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Detalhes bibliográficos
Main Authors: Biankin, Andrew V, Grimmond, Sean M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706765/
https://ncbi.nlm.nih.gov/pubmed/23445765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm423
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