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Thrombospondin-1 is a CD47-dependent endogenous inhibitor of hydrogen sulfide signaling in T cell activation

Thrombospondin-1 is a potent suppressor of T cell activation via its receptor CD47. However, the precise mechanism for this inhibition remains unclear. Because H(2)S is an endogenous potentiator of T cell activation and is necessary for full T cell activation, we hypothesized that thrombospondin-1 s...

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Detalhes bibliográficos
Main Authors: Miller, Thomas W., Kaur, Sukhbir, Ivins-O’Keefe, Kelly, Roberts, David D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706541/
https://ncbi.nlm.nih.gov/pubmed/23499828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2013.02.009
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