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The analysis of DNA adducts: The transition from (32)P-postlabeling to mass spectrometry

The technique of (32)P-postlabeling, which was introduced in 1982 for the analysis of DNA adducts, has long been the method of choice for in vivo studies because of its high sensitivity as it requires only <10 μg DNA to achieve the detection of 1 adduct in 10(10) normal bases. (32)P-postlabeling...

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Detalhes bibliográficos
Main Authors: Klaene, Joshua J., Sharma, Vaneet K., Glick, James, Vouros, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706510/
https://ncbi.nlm.nih.gov/pubmed/22960573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2012.08.007
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