The Asymmetric Binding of PGC-1α to the ERRα and ERRγ Nuclear Receptor Homodimers Involves a Similar Recognition Mechanism

BACKGROUND: PGC-1α is a crucial regulator of cellular metabolism and energy homeostasis that functionally acts together with the estrogen-related receptors (ERRα and ERRγ) in the regulation of mitochondrial and metabolic gene networks. Dimerization of the ERRs is a pre-requisite for interactions wit...

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Detalhes bibliográficos
Main Authors: Takacs, Maria, Petoukhov, Maxim V., Atkinson, R. Andrew, Roblin, Pierre, Ogi, François-Xavier, Demeler, Borries, Potier, Noelle, Chebaro, Yassmine, Dejaegere, Annick, Svergun, Dmitri I., Moras, Dino, Billas, Isabelle M. L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706463/
https://ncbi.nlm.nih.gov/pubmed/23874451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067810
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