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The homeobox protein Prox1 is a negative modulator of ERRα/PGC-1α bioenergetic functions

Estrogen-related receptor α (ERRα) and proliferator-activated receptor γ coactivator-1α (PGC-1α) play central roles in the transcriptional control of energy homeostasis, but little is known about factors regulating their activity. Here we identified the homeobox protein prospero-related homeobox 1 (...

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Autores principales: Charest-Marcotte, Alexis, Dufour, Catherine R., Wilson, Brian J., Tremblay, Annie M., Eichner, Lillian J., Arlow, Daniel H., Mootha, Vamsi K., Giguère, Vincent
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841331/
https://ncbi.nlm.nih.gov/pubmed/20194433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1871610
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