Partially Silencing Brain Toll-Like Receptor 4 Prevents in Part Left Ventricular Remodeling with Sympathoinhibition in Rats with Myocardial Infarction-Induced Heart Failure

BACKGROUND: Left ventricular (LV) remodeling and activation of sympathetic nervous system (SNS) are cardinal features of heart failure. We previously demonstrated that enhanced central sympathetic outflow is associated with brain toll-like receptor 4 (TLR4) probably mediated by brain angiotensin II...

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Autores principales: Ogawa, Kiyohiro, Hirooka, Yoshitaka, Kishi, Takuya, Ide, Tomomi, Sunagawa, Kenji
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706428/
https://ncbi.nlm.nih.gov/pubmed/23874864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069053
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