Circulating angiotensin II deteriorates left ventricular function with sympathoexcitation via brain angiotensin II receptor

Sympathoexcitation contributes to the progression of heart failure. Activation of brain angiotensin II type 1 receptors (AT(1)R) causes central sympathoexcitation. Thus, we assessed the hypothesis that the increase in circulating angiotensin II comparable to that reported in heart failure model affe...

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Bibliographic Details
Published in:Physiol Rep
Main Authors: Shinohara, Keisuke, Kishi, Takuya, Hirooka, Yoshitaka, Sunagawa, Kenji
Format: Artigo
Language:Inglês
Published: John Wiley & Sons, Ltd 2015
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4562594/
https://ncbi.nlm.nih.gov/pubmed/26290529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12514
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