Resistance Mutations and CTL Epitopes in Archived HIV-1 DNA of Patients on Antiviral Treatment: Toward a New Concept of Vaccine

Eleven patients responding successfully to first-line antiretroviral therapy (ART) were investigated for proviral drug resistance mutations (DRMs) in RT by ultra-deep pyrosequencing (UDPS). After molecular typing of the class I alleles A and B, the CTL epitopes in the Gag, Nef and Pol regions of the...

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Autores principales: Papuchon, Jennifer, Pinson, Patricia, Lazaro, Estibaliz, Reigadas, Sandrine, Guidicelli, Gwendaline, Taupin, Jean-Luc, Neau, Didier, Fleury, Hervé
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706427/
https://ncbi.nlm.nih.gov/pubmed/23874854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069029
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