Combination Therapy of VEGF-Trap and Gemcitabine Results in Improved Anti-Tumor Efficacy in a Mouse Lung Cancer Model

BACKGROUND: Angiogenesis is essential for the growth and metastasis of cancer. Although anti-angiogenic agents, particularly vascular endothelial growth factor (VEGF) inhibitors, have exhibited single-agent activity, there is considerable interest in combining these novel drugs with conventional che...

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Main Authors: Zhou, Shuang, Yang, Yang, Yang, Yaoqin, Tao, Huihong, Li, Dong, Zhang, Junli, Jiang, Gening, Fang, Jianmin
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706404/
https://ncbi.nlm.nih.gov/pubmed/23874680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068589
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