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Tyrosine Y189 in the Substrate Domain of the Adhesion Docking Protein NEDD9 Is Conserved with p130Cas Y253 and Regulates NEDD9-Mediated Migration and Focal Adhesion Dynamics

The focal adhesion docking protein NEDD9/HEF1/Cas-L regulates cell migration and cancer invasion. NEDD9 is a member of the Cas family of proteins that share conserved overall protein-protein interaction domain structure, including a substrate domain that is characterized by extensive tyrosine (Y) ph...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Baquiran, Jaime B., Bradbury, Peta, O'Neill, Geraldine M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706375/
https://ncbi.nlm.nih.gov/pubmed/23874939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069304
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