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NEDD9 Stabilizes Focal Adhesions, Increases Binding to the Extra-Cellular Matrix and Differentially Effects 2D versus 3D Cell Migration

The speed of cell migration on 2-dimensional (2D) surfaces is determined by the rate of assembly and disassembly of clustered integrin receptors known as focal adhesions. Different modes of cell migration that have been described in 3D environments are distinguished by their dependence on integrin-m...

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Detalhes bibliográficos
Main Authors: Zhong, Jessie, Baquiran, Jaime B., Bonakdar, Navid, Lees, Justin, Ching, Yu Wooi, Pugacheva, Elena, Fabry, Ben, O'Neill, Geraldine M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324407/
https://ncbi.nlm.nih.gov/pubmed/22509381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035058
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