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Chimeric antigen receptor-engineered T cells for cancer immunotherapy: progress and challenges

Recent years have witnessed much progress in both basic research and clinical trials regarding cancer immunotherapy with chimeric antigen receptor (CAR)-engineered T cells. The unique structure of CAR endows T cell tumor specific cytotoxicity and resistance to immunosuppressive microenvironment in c...

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Detalhes bibliográficos
Main Authors: Han, Ethan Q, Li, Xiu-ling, Wang, Chun-rong, Li, Tian-fang, Han, Shuang-yin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706354/
https://ncbi.nlm.nih.gov/pubmed/23829929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-6-47
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