Pilicides inhibit the FGL chaperone/usher assisted biogenesis of the Dr fimbrial polyadhesin from uropathogenic Escherichia coli

BACKGROUND: The global spread of bacterial resistance has given rise to a growing interest in new anti-bacterial agents with a new strategy of action. Pilicides are derivatives of ring-fused 2-pyridones which block the formation of the pili/fimbriae crucial to bacterial pathogenesis. They impair by...

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Main Authors: Piatek, Rafał, Zalewska-Piatek, Beata, Dzierzbicka, Krystyna, Makowiec, Sławomir, Pilipczuk, Justyna, Szemiako, Kasjan, Cyranka-Czaja, Anna, Wojciechowski, Marek
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706281/
https://ncbi.nlm.nih.gov/pubmed/23758700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-13-131
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