Cannabinoid receptor (CNR1) genotype moderates the effects of childhood physical abuse on anhedonia and depression

CONTEXT: The endocannabinoid system has been implicated in stress adaptation and the regulation of mood in rodent studies, but few human association studies have examined these links and replications are limited. OBJECTIVE: To examine whether a synonymous polymorphism, rs1049353, in exon 4 of the ge...

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Detalhes bibliográficos
Main Authors: Agrawal, Arpana, Nelson, Elliot C., Littlefield, Andrew K., Bucholz, Kathleen K., Degenhardt, Louisa, Henders, Anjali K., Madden, Pamela A.F., Martin, Nicholas G., Montgomery, Grant W., Pergadia, Michele L., Sher, Kenneth J., Heath, Andrew C., Lynskey, Michael T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706194/
https://ncbi.nlm.nih.gov/pubmed/22393204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archgenpsychiatry.2011.2273
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