Cannabinoid receptor (CNR1) genotype moderates the effects of childhood physical abuse on anhedonia and depression

CONTEXT: The endocannabinoid system has been implicated in stress adaptation and the regulation of mood in rodent studies, but few human association studies have examined these links and replications are limited. OBJECTIVE: To examine whether a synonymous polymorphism, rs1049353, in exon 4 of the ge...

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Autors principals: Agrawal, Arpana, Nelson, Elliot C., Littlefield, Andrew K., Bucholz, Kathleen K., Degenhardt, Louisa, Henders, Anjali K., Madden, Pamela A.F., Martin, Nicholas G., Montgomery, Grant W., Pergadia, Michele L., Sher, Kenneth J., Heath, Andrew C., Lynskey, Michael T.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706194/
https://ncbi.nlm.nih.gov/pubmed/22393204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archgenpsychiatry.2011.2273
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