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Multiple Genetic Variant Association Testing by Collapsing and Kernel Methods With Pedigree or Population Structured Data

Searching for rare genetic variants associated with complex diseases can be facilitated by enriching for diseased carriers of rare variants by sampling cases from pedigrees enriched for disease, possibly with related or unrelated controls. This strategy, however, complicates analyses because of shar...

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Detalhes bibliográficos
Main Authors: Schaid, Daniel J., McDonnell, Shannon K., Sinnwell, Jason P., Thibodeau, Stephen N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706099/
https://ncbi.nlm.nih.gov/pubmed/23650101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21727
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