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Spirohexenolide A Targets Human Macrophage Migration Inhibitory Factor (hMIF)

Spirohexenolides A and B comprise a unique family of spirotetronate natural products. We report on the identification of their binding to and modulation of human macrophage migration inhibitor factor (hMIF). Using an immunoaffinity–fluorescent labeling method, the properties of this interaction are...

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Detalhes bibliográficos
Main Authors: Yu, Wei–Lun, Jones, Brian D., Kang, MinJin, Hammons, Justin C., La Clair, James J., Burkart, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706094/
https://ncbi.nlm.nih.gov/pubmed/23659282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np3004497
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