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Multiple post-translational modifications regulate E-cadherin transport during apoptosis

E-cadherin is synthesized as a precursor and then undergoes cleavage by proprotein convertases. This processing is essential for E-cadherin maturation and cell adhesion. Loss of cell adhesion causes detachment-induced apoptosis, which is called anoikis. Anoikis can be inhibited despite loss of cell–...

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書目詳細資料
Main Authors: Geng, Fei, Zhu, Weijia, Anderson, Richard A., Leber, Brian, Andrews, David W.
格式: Artigo
語言:Inglês
出版: Company of Biologists 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706076/
https://ncbi.nlm.nih.gov/pubmed/22375065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.096735
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