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Slit-2 repels the migration of olfactory ensheathing cells by triggering Ca(2+)-dependent cofilin activation and RhoA inhibition
Olfactory ensheathing cells (OECs) migrate from the olfactory epithelium towards the olfactory bulb during development. However, the guidance mechanism for OEC migration remains a mystery. Here we show that migrating OECs expressed the receptor of the repulsive guidance factor Slit-2. A gradient of...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Company of Biologists
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3705990/ https://ncbi.nlm.nih.gov/pubmed/21187345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.071357 |
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