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Polymorphic transporters and platinum pharmacodynamics

Several solute carriers and ATP-binding cassette transporters have been implicated in the influx or efflux of platinum-based chemotherapeutic agents such as cisplatin, carboplatin, and oxaliplatin. Given that many of these proteins are highly polymorphic, the genetic status of these proteins could b...

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Detalhes bibliográficos
Main Authors: Sprowl, Jason A., Ness, Rachel A., Sparreboom, Alex
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3705946/
https://ncbi.nlm.nih.gov/pubmed/22986709
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