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Crystal structure of a monomeric retroviral protease solved by protein folding game players

Following the failure of a wide range of attempts to solve the crystal structure of M-PMV retroviral protease by molecular replacement, we challenged players of the protein folding game Foldit to produce accurate models of the protein. Remarkably, Foldit players were able to generate models of suffi...

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Dettagli Bibliografici
Autori principali: Khatib, Firas, DiMaio, Frank, Cooper, Seth, Kazmierczyk, Maciej, Gilski, Miroslaw, Krzywda, Szymon, Zabranska, Helena, Pichova, Iva, Thompson, James, Popovi, Zoran, Jaskolski, Mariusz, Baker, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3705907/
https://ncbi.nlm.nih.gov/pubmed/21926992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2119
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