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Posttranslational Nitration of Tyrosine Residues Modulates Glutamate Transmission and Contributes to N-Methyl-D-aspartate-Mediated Thermal Hyperalgesia

Activation of the N-methyl-D-aspartate receptor (NMDAR) is fundamental in the development of hyperalgesia. Overactivation of this receptor releases superoxide and nitric oxide that, in turn, forms peroxynitrite (PN). All of these events have been linked to neurotoxicity. The receptors and enzymes in...

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Detalhes bibliográficos
Main Authors: Muscoli, Carolina, Dagostino, Concetta, Ilari, Sara, Lauro, Filomena, Gliozzi, Micaela, Bardhi, Erlisa, Palma, Ernesto, Mollace, Vincenzo, Salvemini, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3705874/
https://ncbi.nlm.nih.gov/pubmed/23864769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/950947
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