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Weakness of whole muscles in mice deficient in Cu, Zn superoxide dismutase is not explained by defects at the level of the contractile apparatus
Mice deficient in Cu,Zn superoxide dismutase (Sod1(−/−) mice) demonstrate elevated oxidative stress associated with rapid age-related declines in muscle mass and force. The decline in mass for muscles of Sod1(−/−) mice is explained by a loss of muscle fibers, but the mechanism underlying the weaknes...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer Netherlands
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3705120/ https://ncbi.nlm.nih.gov/pubmed/22696118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-012-9441-7 |
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