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Weakness of whole muscles in mice deficient in Cu, Zn superoxide dismutase is not explained by defects at the level of the contractile apparatus

Mice deficient in Cu,Zn superoxide dismutase (Sod1(−/−) mice) demonstrate elevated oxidative stress associated with rapid age-related declines in muscle mass and force. The decline in mass for muscles of Sod1(−/−) mice is explained by a loss of muscle fibers, but the mechanism underlying the weaknes...

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Hlavní autoři: Larkin, Lisa M., Hanes, Michael C., Kayupov, Erdan, Claflin, Dennis R., Faulkner, John A., Brooks, Susan V.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Netherlands 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3705120/
https://ncbi.nlm.nih.gov/pubmed/22696118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-012-9441-7
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