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p27Kip1 Knockdown Induces Proliferation in the Organ of Corti in Culture after Efficient shRNA Lentiviral Transduction

The cells in the organ of Corti do not exhibit spontaneous cell regeneration; hair cells that die after damage are not replaced. Supporting cells can be induced to transdifferentiate into hair cells, but that would deplete their numbers, therefore impairing epithelium physiology. The loss of p27Kip1...

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Detalhes bibliográficos
Main Authors: Maass, Juan C., Berndt, F. Andrés, Cánovas, José, Kukuljan, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3705079/
https://ncbi.nlm.nih.gov/pubmed/23612739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10162-013-0383-2
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