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Killing of intracellular Leishmania donovani by lymphokine-stimulated human mononuclear phagocytes. Evidence that interferon-gamma is the activating lymphokine.

We have found that the crude lymphokines, which prime the human monocyte-derived macrophage to generate H2O2 and exert microbicidal activity against intracellular Leishmania donovani, are rich in interferon (IFN)-gamma (600-3,000 U/ml). To determine the role of this specific lymphocyte product in ma...

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Vydáno v:J Clin Invest
Hlavní autoři: Murray, H W, Rubin, B Y, Rothermel, C D
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 1983
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370435/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6415111/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111107
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