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An in vitro model of antibody-enhanced killing of the intracellular parasite Leishmania amazonensis.

Footpad infection of C3HeB/FeJ mice with Leishmania amazonensis leads to chronic lesions accompanied by large parasite loads. Co-infecting these animals with L. major leads to induction of an effective Th1 immune response that can resolve these lesions. This cross-protection can be recapitulated in...

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Autori principali: Katherine N Gibson-Corley, Marie M Bockenstedt, Huijuan Li, Paola M Boggiatto, Yashdeep Phanse, Christine A Petersen, Bryan H Bellaire, Douglas E Jones
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2014-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC4156363?pdf=render
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