Genetic Variants That Confer Resistance to Malaria Are Associated with Red Blood Cell Traits in African-Americans: An Electronic Medical Record-based Genome-Wide Association Study

To identify novel genetic loci influencing interindividual variation in red blood cell (RBC) traits in African-Americans, we conducted a genome-wide association study (GWAS) in 2315 individuals, divided into discovery (n = 1904) and replication (n = 411) cohorts. The traits included hemoglobin conce...

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Autori principali: Ding, Keyue, de Andrade, Mariza, Manolio, Teri A., Crawford, Dana C., Rasmussen-Torvik, Laura J., Ritchie, Marylyn D., Denny, Joshua C., Masys, Daniel R., Jouni, Hayan, Pachecho, Jennifer A., Kho, Abel N., Roden, Dan M., Chisholm, Rex, Kullo, Iftikhar J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Genetics Society of America 2013
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Investigations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3704235/
https://ncbi.nlm.nih.gov/pubmed/23696099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.113.006452
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