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TGF-β type II receptor phosphorylates PTH receptor to integrate bone remodelling signalling
Parathyroid hormone (PTH) regulates calcium homeostasis and bone metabolism by activating PTH type I receptor (PTH1R). Here we show that transforming growth factor (TGF)-β type II receptor (TβRII) forms an endocytic complex with PTH1R in response to PTH and regulates signalling by PTH and TGF-β. TβR...
में बचाया:
मुख्य लेखकों: | , , , , , |
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स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
2010
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3704184/ https://ncbi.nlm.nih.gov/pubmed/20139972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2022 |
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