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Fast and Selective Modification of Thiol Proteins/Peptides by N-(Phenylseleno) phthalimide

We previously reported that selenamide reagents such as ebselen and N-(phenylseleno) phthalimide (NPSP) can be used to selectively derivatize thiols for mass spectrometric analysis, and the introduced selenium tags are useful as they could survive or removed with collision-induced dissociation (CID)...

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Bibliographic Details
Main Authors: Wang, Zhengfang, Zhang, Yun, Zhang, Hao, Harrington, Peter B., Chen, Hao
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3704154/
https://ncbi.nlm.nih.gov/pubmed/22223263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-011-0317-3
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